Targeted tumor detection: guidelines for developing biotinylated diagnostics
نویسندگان
چکیده
منابع مشابه
Diagnostics for Developing Countries
Improving the availability of high quality diagnostic tests for infectious diseases is a global priority. Lack of access by people living in low income countries may deprive them of life saving treatment and reduces opportunities to prevent onward transmission and spread of the disease. Diagnostic laboratories are often poorly resourced in developing countries, and sparsely distributed. Improve...
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A site-specific labeling method was developed in which sulfhydryl groups of a murine IgG2a anti-ovarian monoclonal antibody, 5G6.4, were biotinylated with /V-iodoacetyl-yV'-biotinylhexylenediamine (Compound /) following partial reduction of disulfide bonds with dithiothreitol. Reaction of 7-alkylated 5G6.4 with 125I-streptavidingave immunoreactive streptavidin-/-biotinylated complexes. Radio-fa...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2017
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c7cc00311k